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BNSSG Paediatric Joint Formulary
6.6 Hypothalamic and anterior pituitary hormone related disorders
Last edited: 08-02-2024
6.6.1 Adrenocortical function testing
First line drugs |
Second line drugs |
Specialist drugs |
Secondary care drugs |
Corticotrophins
Tetracosactide (ACTH) (Syncathen test) (TLS Red)
- 1mg/mL to treat infantile spasms
6.6.2 Assessment of pituitary function
Corticorelin (Corticotrophin-releasing hormone, CRH) (TLS Red)
Gonadorelin (TLS Red)
- Used to assess gonadotrophin axis. May be performed as a part of full pituitary function testing
6.6.4 Growth hormone disorders
Somatropin (synthetic Human Growth Hormone) (TLS Red)
- NICE TA188 Human growth hormone (somatropin) for the treatment of growth failure in children
- Via Homecare at BRCH
Somatrogon (TLS Red)
- NICE TA863 Somatrogon for treating growth disturbance in children and young people aged 3 years and over
Somatorelin (GHRH) (TLS Red)
- To test for growth hormone deficiency
Arginine (TLS Red)
- Combined somatorelin (GHRH)-arginine test Occasional investigation in children suspected of growth hormone deficiency
Lanreotide (TLS Red)
Pegmivosant (TLS Red)
6.6.5 Insulin-like growth factor-I deficiency
Specific Indication:
Mecasermin (TLS Red)