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BNSSG Paediatric Joint Formulary

5.3 Fungal infection

Last edited: 14-02-2024

5.3 Fungal infection

First line drugs Second line drugs Specialist drugs Secondary care drugs

 

Antifungals

Terbinafine (oral) (TLS Green)

Alternatives:

Griseofulvin (oral) (TLS Blue)

 

Echinocandin Antifungals

Micafungin (parenteral) (TLS Red)

  • Secondary care restricted, see local guidelines

Caspofungin (parenteral) (TLS Red)

  • Secondary care restricted, see local guidelines

 

Fluorinated Pyrimidine Antifungals

Flucytosine (oral & parenteral) (TLS Red)

  • Secondary care restricted, see local guidelines

 

Polyene Antifungals

Liposomal amphotericin (parenteral) (TLS Red)

  • Restricted, see local guidelines
  • The National Patient Safety Agency has advised all healthcare staff involved in the use of intravenous amphotericin of the potentially lethal results if non-lipid and lipid formulations of the drug are confused
  • Caution: double check

 

Triazole Antifungals

Fluconazole (oral) (TLS Green)

Alternatives:

Itraconazole (oral) (TLS Blue)

Fluconazole (parenteral) (TLS Red)

  • Restricted, see local guidelines

Voriconazole (oral & parenteral) (TLS Red)

  • Secondary care restricted, see local guidelines

Posaconazole (oral) (TLS Red)

  • Secondary care restricted, see local guidelines

 

5.3.1 Pneumocystis pneumonia

Co-trimoxazole (parenteral & oral) (TLS Red)

  • Secondary care restricted, see local guidelines

Atovaquone (oral) (TLS Red)

  • Secondary care restricted, see local guidelines

Dapsone (oral) (TLS Red)

  • Secondary care restricted, see local guidelines

Pentamidine (parenteral & nebulised) (TLS Red)

  • Secondary care restricted, see local guidelines

Primaquine (oral) (unlicensed) (TLS Red)

  • Secondary care restricted, see local guidelines