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BNSSG Paediatric Joint Formulary

3.2 Allergic conditions

Last edited: 15-04-2024

3.2 Allergic conditions

First line drugs Second line drugs Specialist drugs Secondary care drugs

 

Antihistamines

Cetirizine (TLS Green)

Chlorphenamine (TLS Green)

Loratadine (TLS Green)

Alternative

Fexofenadine (TLS Blue)

Specific indications:

Promethazine (TLS Blue)

Hydroxyzine (TLS Green)

 

Allergen Immunotherapy

Refer to Immunology

 

Bee and Wasp Allergen Extracts

Alutard® (TLS Red)

  • Hypersensitivity to wasp or bee venom only 

  

Grass and Tree Pollen Extracts

Specific Indications: (TLS Red)

Pollinex Quattro® (TLS Red)

  • Immunology only

Grazax® (TLS Red)

  • Immunology only

 

Grass, Tree Pollen and House Dust mite Extracts

OralVac® (TLS Red)

  • Immunology only

Acarizax (oral) (TLS Red)

  • For adolescents and adults with severe rhinitis or house dust mite allergic asthma

 

Birch Pollen Extract

Itulazax (Standardised allergen extract of pollen from white birch [Betula verrucosa]) (TLS Red)

  • For treatment of moderate-to-severe allergic rhinitis and/or conjunctivitis induced by pollen from the birch homologous group for use by the specialist allergy team.

 

Peanut Allergy

Palforzia (TLS Red)

  • NICE TA769 Palforzia for treating peanut allergy in children and young people

 

Allergic Emergencies

See  BNSSG Remedy Adrenaline Auto-Injectors page for further information from UHBW Children's hospital

 

Anaphylaxis

Recommended: (TLS Green)

Adrenaline (epinephrine) 1 in 1000 (1mg/mL) (TLS Green)

  • Intramuscular

  • For self-administration using pre-filled adrenaline auto-injectors (pens), brands include Epipen®, Jext® and Emerade® (note: in May 2023 a National Patient Safety Alert (NatPSA) Class 1 Medicines Recall Notification was published recalling Emerade 500 micrograms and Emerade 300 micrograms auto-injectors, due to the potential for device failure, NatPSA/2023/004/MHRA)

Adrenaline (epinephrine) 1 in 10,000 (100micrograms/mL) (TLS Green) IV

  • Intravenous

Chlorphenamine (parenteral) (TLS Green)

Hydrocortisone sodium succinate (parenteral) (TLS Green)

 

3.2.1 Angioedema

Angioedema

C1-esterase inhibitor (Berinert®) (TLS Red)

 

Respiratory Stimulants

Doxapram (TLS Red)