For women experiencing migraine, transdermal estrogens should be used.
Migraines are often triggered by fluctuation in hormone levels. A patch provides a stable release of hormones and therefore is the preferred option.
Use the lowest dose of estrogen that controls vasomotor symptoms. Start with a low dose and increase gradually if required.
Where progestogen is required, continuous delivery is recommended, with preparations such as: 52mg levonorgestrel intrauterine device, transdermal norethisterone (as in combined patches), micronised progesterone.
The BMS has produced helpful guidance on HRT prescribing in people with migraine available here: 06-BMS-TfC-Migraine-and-HRT-NOV2022-A.pdf (thebms.org.uk)
18-WHC-FACTSHEET-Migraine-and-HRT-NOV2023-B.pdf (womens-health-concern.org)
Migraine, menopause and HRT - National Migraine Centre
Headaches, migraines and the menopause explained - a British Menopause Society video (youtube.com)
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