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BNSSG Paediatric Joint Formulary

9.1 Anaemia and some other blood disorders

Last edited: 19-04-2024

First line drugs Second line drugs Specialist drugs Secondary care drugs

9.1.2 Anaemias, G6PD deficiency

Please refer to BNF for drugs to avoid in G6PD deficiency

 

9.1.3 Anaemias, hypoplastic, haemolytic and renal

Epoetins

Darbepoetin alfa (TLS Red)

  • For use by Renal, Haematology & Oncology only
  • Oncology use see NICE TA323 Erythropoietin (alfa and beta) and darbepoetin for the treatment of cancer-treatment induced anaemia (including review of NICE TA142)

Erythropoietin (Epoetin) beta (TLS Red)

  • For use by Renal, Haematology & Oncology only
  • Oncology use see NICE TA323 Erythropoietin (alfa and beta) and darbepoetin for the treatment of cancer-treatment induced anaemia (including review of NICE TA142)

 

Monoclonal Antibodies

Eculizumab (TLS Red)

 

9.1.4 Anaemias, iron-deficiency

Iron (Injectable)

  • Please see MHRA Drug Safety Update August 2013 regarding new strengthened recommendations to manage and minimise risk of serious hypersensitivity reactions
  • Anaphylactoid reactions can occur with parenteral administration of iron complexes. Facilities for cardio-pulmonary resuscitation must be at hand

Specific indication: 

Ferric carboxymaltose (Ferinject®) (TLS Red)

  • For use in Gastroenterology and Medical patients

Iron sucrose (Venofer®) (TLS Red)

  • For use in Renal patients

Alternative:

Iron dextran (CosmoFer®) (TLS Red)

Ferric derisomaltose (previously known as Monofer®) (TLS Red)

  • UHB only, day case patients only

 

Iron (Oral)

Ferrous sulphate (TLS Green)

Ferrous fumarate (TLS Green)

Sodium feredetate elixir (Sytron®) (TLS Green)

Ferrous fumarate / Folic acid tablet (Pregaday®) (TLS Green)

  • Ferrous gluconate or sodium feredetate may be used when patients are unable to tolerate other oral iron preparations

 Alternatives:

Ferrous gluconate tablet (TLS Blue)

 

9.1.5 Anaemias, megaloblastic

Folates

Folic acid (TLS Green)

 

Vitamin B Group

Hydroxocobalamin intramuscular injection (TLS Amber)

  • Disorders of cobalamin metabolism

Specific indication:

Cyanocobalamin (TLS Blue)

  • Vitamin-B12 deficiency of dietary origin
  • Please refer to BNF for guidance on the use of folic acid for prophylaxis in pregnancy and prevention of neural tube defects