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BNSSG Adult Joint Formulary
16.6 End of life symptom control- Palliative Care
Last edited: 22-05-2025
First line drugs |
Second line drugs |
Specialist drugs |
Secondary care drugs |
For guidance, see local guidelines
Discontinue non-essential medications and ensure PRN medication is prescribed to address the symptoms below.
Pain
Morphine sulphate injection (TLS Green)
Diamorphine injection (TLS Blue)
Oxycodone injection (TLS Blue)
- If morphine/diamorphine intolerant
Fentanyl injection (TLS Blue)
Alfentanil injection (TLS Blue)
- If renal impairment/morphine intolerant under guidance from palliative care team
Clonazepam (TLS Blue)
Nausea and Vomiting
Metoclopramide (TLS Green)
Cyclizine (TLS Green)
Haloperidol (TLS Blue)
Levomepromazine (TLS Blue)
Ondansetron subcutaneous/intravenous injection (TLS Blue)
- For chemotherapy/radiotherapy/post surgery induced vomiting
Respiratory Tract Secretions
Hyoscine butylbromide (TLS Green)
Glycopyrronium bromide (TLS Blue)
Hyoscine hydrobromide (TLS Blue)
Terminal Restlessness and Agitation
Midazolam (TLS Green)
Haloperidol (TLS Green)
Levomepromazine subcutaneous injection (TLS Blue)
Phenobarbital (TLS Amber Specialist Recommended)
Seizures
Clonazepam (TLS Amber Specialist Recommended)
Phenobarbital (TLS Amber Specialist Recommended)
Levetiracetam (TLS Amber Specialist Recommended)
Other
Dexamethasone (TLS Amber Specialist Recommended)
Octreotide (TLS Red)
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