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BNSSG Adult Joint Formulary
16.4 Anxiety, depression and confusion- Palliative Care
Last edited: 22-05-2025
First line drugs |
Second line drugs |
Specialist drugs |
Secondary care drugs |
This section does not include terminal agitation. For agitation in the last days of life, see chapter 16.6
Insomnia
See chapter 4.7 for formulary options
Severe anxiety
Diazepam (TLS Green)
Lorazepam (TLS Green)
Depression
Once full assessment and appropriate psychological support has been addressed, consider trial of antidepressant medication
Sertraline (TLS Green)
Citalopram (TLS Green)
Mirtazapine (TLS Blue)
Delirium and Agitation
Ensure reversible causes have been investigated and appropriately treated
Haloperidol (TLS Green)
Lorazepam (TLS Green)
- Tablets and injection
- If distress is predominant
Quetiapine (TLS Amber Specialist Recommended)
Olanzapine (TLS Amber Specialist Recommended)
Risperidone (TLS Amber Specialist Recommended)
Levomepromazine (oral) (TLS Amber Specialist Recommended)
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